Titanium dioxide nanoparticles (TiO2NPs) widely are used in animal and poultry industries. Application of these particles can led to apoptosis, oxidative damages, immune/inflammatory responses, histopathological changes and affect transcription, translation, cell cycle and differentiation. Detoxification of endogenous and exogenous toxins is catalyzed by cytochrome P450s (CYPs) in the cell. CYP1A ...